mercoledì 6 maggio 2009

Oil and breast cancer

Olive oil could become an excellent 'dressing' for the chemotherapy to combat breast cancer, while improving their efficiency and preventing the creation of resistance farmacologiche.E 'the new perspective offered by the therapeutic results of experiments Javier Menendez of Northwestern University Feinberg School of Medicine in Chicago have revealed that the mechanism of action of anti-cancer. According to the Annals of Oncology, the fats of the oil drop by 46 percent the levels of one of the major oncogenes cause of breast cancer and enhance the operation of a drug that targets this oncogene.Cio 'explains the lower risk for this cancer typical of women in Mediterranean countries, as demonstrated in the past with many epidemiological investigations on samples of the female population. The researchers arrived at these first biochemical explanation, now aiming to set new epidemiological investigations to see if the sick women who use the extra table to respond better to treatment oncologiche.In a second time you can 'even think to include molecules base oil as adjuvant therapy stesse.Gli scholars have wanted to investigate why the protective effects of traditional golden sauce of the Mediterranean countries to find the reason for the lower spread of breast cancer in the south of Europe. Cosi 'experts have studied the effect of oil, the main molecule dell'extravergine on diseased cells grown in the laboratory. Oleic acid is effective against cancer cells because 'reduces by 46% the activity' of the gene HER-2/neu, an oncogene that 'ruinous hyperactive in one out of five cases of breast cancer and whose hyperactivity' and ' linked to cancer prognosis with most 'delicata.Inoltre researchers have discovered that oleic acid interacts with the drug' Herceptin ', a monoclonal antibody that recognizes and binds, trapped, the protein produced from its HER-2/neu. And, if it 'were not enough to place the confidence of extra charge on Cancer, the oleic acid stimulates the activity' of a tumor gene, or a brake of the natural growth of the tumor used to produce the protein p27Kip1. Molecule and this' in turn important because 'prevents the patient to become resistant all'erceptina. Oleic acid, and then, and' protection for women, acting on several 'fronts. So now the researchers aim to determine whether the presence of oil in the diet of the patient enhances the effectiveness of cancer therapies which it undergoes and away the risk of resistance all'herceptin. At a later time, researchers have concluded, with animal testing may be developed providing for the addition of oleic in drug therapies against breast cancer, to make themselves more therapies' effectiveness and reduce the risk of drug resistance.

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